SLC29A3 Rabbit Polyclonal Antibody

CAT#: TA349153

Rabbit Polyclonal Anti-SLC29A3 Antibody

Product Images

Western blot analysis of SLC29A3 in mouse bladder tissue lysate with SLC29A3 antibody at 1 ug/mL.

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  Immunohistochemistry of SLC29A3 in rat colon tissue with SLC29A3 antibody at 5 ug/mL.

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  Immunofluorescence of SLC29A3 in rat colon muscle tissue with SLC29A3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SLC29A3 antibody was raised against a 19 amino acid peptide near the amino terminus of human SLC29A3.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SLC29A3 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 52 kDa; Observed: 57 kDa
• Gene Name: solute carrier family 29 member 3
• Database Link:
  NP_060814
  Entrez Gene 71279 MouseEntrez Gene 353307 RatEntrez Gene 55315 Human
  UniProt ID Q9BZD2
• Background: SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter (3). Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism (4). A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus (5).
• Synonyms: ENT3; HCLAP; HJCD; PHID

Reference Data

• Protein Families: Transmembrane