WDR61 Rabbit Polyclonal Antibody

CAT#: TA349107

Rabbit Polyclonal Anti-WDR61 Antibody

Product Images

Western blot analysis of WDR61 in SK-N-SH cell lysate with WDR61 antibody at 1 ug/mL.

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  Immunohistochemistry of WDR61 in mouse brain tissue with WDR61 antibody at 5 ug/mL.

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  Immunofluorescence of WDR61 in mouse brain tissue with WDR61 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: WDR61 antibody was raised against a 14 amino acid peptide near the amino terminus of human WDR61.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: WDR61 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 34 kDa; Observed: 30 kDa
• Gene Name: WD repeat domain 61
• Database Link:
  NP_079510
  Entrez Gene 66317 MouseEntrez Gene 363064 RatEntrez Gene 80349 Human
  UniProt ID Q9GZS3
• Background: WDR61 (WD-repeat-containing protein 61), also known as SKI8 or REC14, is a subunit of the human PAF and SKI complexes, which function in transcriptional regulation and are involved in events downstream of RNA synthesis, such as RNA surveillance (1,2). PAF1C is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1C (3,4).
• Synonyms: REC14; SKI8

Reference Data

• Protein Pathways: RNA degradation