ANGPTL3 Rabbit Polyclonal Antibody

CAT#: TA349065

Rabbit Polyclonal Anti-ANGPTL3 Antibody

Product Images

Western blot analysis of ANGPTL3 in human heart tissue lysate with ANGPTL3 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of ANGPTL3 in rat heart tissue with ANGPTL3 antibody at 5 ug/mL.

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  Immunofluorescence of ANGPTL3 in rat heart tissue with ANGPTL3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ANGPTL3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ANGPTL3.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: ANGPTL3 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 51 kDa; Observed: 53 kDa
• Gene Name: angiopoietin like 3
• Database Link:
  NP_055310
  Entrez Gene 27329 Human
  UniProt ID Q9Y5C1
• Background: The angiopoietin-related protein 3 (ANGPTL3) is a member of a family of secreted proteins that function in angiogenesis (1). ANGPTL3 is processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis (2,3). Recent experiments have shown that a deficiency of ANGPTL3 is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids, suggesting that ANGPTL3 may also play a role in modulating glucose metabolism (4).
• Synonyms: GP91-2; MOX1; NOH-1; NOH1