Cyclin D2 (CCND2) Rabbit Polyclonal Antibody

CAT#: TA348917

Rabbit Polyclonal Anti-Cyclin D2 (Phospho-Thr280) Antibody

Product Images

Western blot analysis of Cyclin D2 (Phospho-Thr280) expression in 293 cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Cyclin D2 (Phospho-Thr280) Antibody: A synthesized peptide derived from human Cyclin D2 (Phospho-Thr280)
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 33 kDa
• Gene Name: cyclin D2
• Database Link:
  NP_001750
  Entrez Gene 12444 MouseEntrez Gene 64033 RatEntrez Gene 894 Human
  UniProt ID P30279
• Background: Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.
• Synonyms: KIAK0002; MPPH3
• Note: Cyclin D2 (Phospho-Thr280) Antibody detects endogenous levels of total Cyclin D2 (Phospho-Thr280)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Focal adhesion, Jak-STAT signaling pathway, p53 signaling pathway, Wnt signaling pathway