VEGF Receptor 2 (KDR) Rabbit Polyclonal Antibody

CAT#: TA348416

Rabbit Polyclonal Anti-Phospho-VEGFR2(Tyr1214) Antibody

Product Images

Western blot analysis on K562 cell lysate using Phospho-VEGFR2 (Tyr1214) Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Phospho-VEGFR2(Tyr1214) Antibody: A synthesized peptide derived from human VEGFR2 around the phosphorylation site of Tyrosine 1214
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 152 kDa
• Gene Name: kinase insert domain receptor
• Database Link:
  NP_002244
  Entrez Gene 16542 MouseEntrez Gene 25589 RatEntrez Gene 3791 Human
  UniProt ID P35968
• Background: VEGFR-2 is a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2. Plays a key role in vascular development and regulation of vascular permeability.
• Synonyms: CD309; FLK1; VEGFR; VEGFR2
• Note: Phospho-VEGFR2(Tyr1214) Antibody detects endogenous levels of VEGFR2 only when phosphorylated at Tyrosine 1214

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, VEGF signaling pathway