Transglutaminase 2 (TGM2) Rabbit Polyclonal Antibody

CAT#: TA347654

Rabbit Polyclonal Anti-TGM2 Antibody

Product Images

Western blot analysis on HuvEc cell lysate using TGM2 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-TGM2 Antibody: A synthesized peptide derived from human TGM2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 77 kDa
• Gene Name: transglutaminase 2
• Database Link:
  NP_004604
  Entrez Gene 21817 MouseEntrez Gene 7052 Human
  UniProt ID P21980
• Background: TGM2 an enzyme of the transglutaminase family that catalyzes the crosslinking of proteins and the conjugation of polyamines to proteins. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. . Is the autoantigen in coeliac disease and plays a role in apoptosis, cellular differentiation and matrix stabilisation.
• Synonyms: G-ALPHA-h; GNAH; HEL-S-45; TG2; TGC
• Note: TGM2 Antibody detects endogenous levels of TGM2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Huntington's disease