Cyclin A1 (CCNA1) Rabbit Polyclonal Antibody

CAT#: TA347365

Rabbit Polyclonal Anti-Cyclin A1 Antibody

Product Images

Western blot analysis on SK-OV3 cell lysate using Cyclin A1 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Cyclin A1 Antibody: A synthesized peptide derived from human Cyclin A1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 52 kDa
• Gene Name: cyclin A1
• Database Link:
  NP_003905
  Entrez Gene 12427 MouseEntrez Gene 295052 RatEntrez Gene 8900 Human
  UniProt ID P78396
• Background: CCNA1 May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells. Belongs to the cyclin family. Cyclin AB subfamily. Interacts with the CDK2 and the CDC2 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. Does not bind CDK4 and CDK5 (in vitro). The cyclin A1-CDK2 complex interacts with transcription factor E2F-1 and RB proteins.
• Synonyms: CT146
• Note: Cyclin A1 antibody detects endogenous levels of total Cyclin A1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Acute myeloid leukemia, Cell cycle, Pathways in cancer, Progesterone-mediated oocyte maturation