WDR77 Mouse Monoclonal Antibody [Clone ID: 8A10-C10-E8]

CAT#: TA347002

Mouse Monoclonal WDR77 Antibody

Specifications

Product Data

• Clone Name: 8A10-C10-E8
• Applications: IF, WB
• Recommended Dilution: WB: 1:1000, IF: 1:100
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for MEP50/WDR77 antibody: purified recombinant human WDR77 protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 42 kDa
• Gene Name: WD repeat domain 77
• Database Link:
  NP_077007
  Entrez Gene 70465 MouseEntrez Gene 310769 RatEntrez Gene 79084 Human
  UniProt ID Q9BQA1
• Background: WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex,which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061).This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al.,2002 [PubMed 11756452]). [supplied by OMIM,Mar 2008]
• Synonyms: HKMT1069; MEP-50; MEP50; Mep50; Nbla10071; p44

Reference Data

• Protein Families: Stem cell - Pluripotency