COX4 (COX4I1) Mouse Monoclonal Antibody [Clone ID: 4D11-B3-E8]

CAT#: TA346921

Mouse Monoclonal COX IV Antibody

Product Images

Western blot analysis of COX IV in mouse skeletal muscel and Jurkat lysates using COX IV antibody.

• 

  Western blot analysis of COX IV in Goat muscle, CHO-K1, COS7, 3T3, Hela, C6 and K562 lysates using COX IV antibody.

• 

  Immunohistochemistry analysis of paraffin-embedded Human colorectal carcinoma using COX IV antibody (4D11B3E8).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

• 

  Immunoprecipitation analysis of COX IV (4D11) in Hela lysates using COX IV antibody.

• 

  Flow Cytometry analysis of K562 stained with COX4 (red). Blue line histogram represents the isotype control, normal mouse IgG.

• 

  Immunocytochemistry analysis of COX IV in HeLa cells using COX IV antibody.

Show all 6 images

Specifications

Product Data

• Clone Name: 4D11-B3-E8
• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1:1000, IF: 1:150, FC: 1:100
• Reactivities: Human, Monkey, Mouse, Rat, Hamster, Goat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for COX IV antibody: A synthetic peptide corresponding to carboxyl terminal residues of human COX IV
• Formulation: Purified mouse monoclonal antibody in buffer containing 0.1M Tris-Glycine(pH 7.4,150 mM NaCl)with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 17 kDa
• Gene Name: cytochrome c oxidase subunit 4I1
• Database Link:
  NP_001852
  Entrez Gene 12857 MouseEntrez Gene 29445 RatEntrez Gene 1327 Human
  UniProt ID P13073
• Background: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain.It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane.The complex consists of 13 mitochondrial- and nuclear-encoded subunits.The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities.The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex.This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation,and shares a promoter with it. [provided by RefSeq,Jul 2008]
• Synonyms: COX4; COX4-1; COXIV; COX IV-1; COXIV-1

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease