EMAP II (AIMP1) Rabbit Polyclonal Antibody

CAT#: TA332594

Rabbit anti-AIMP1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using AIMP1 antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human AIMP1
• Formulation: Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: aminoacyl tRNA synthetase complex interacting multifunctional protein 1
• Database Link:
  NP_001135887
  Entrez Gene 13722 MouseEntrez Gene 114632 RatEntrez Gene 9255 Human
  UniProt ID Q12904
• Background: The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.
• Synonyms: EMAP2; EMAPII; HLD3; p43; SCYE1

Reference Data

• Protein Families: Druggable Genome