GRIA1 Rabbit Polyclonal Antibody
Rabbit anti-GRIA1 Polyclonal Antibody
Product Datasheet for 'TA332438'
|Recommend Dilution||WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Recombinant protein of human GRIA1|
|Formulation||Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Predicted Protein Size||906|
|Gene Name||glutamate ionotropic receptor AMPA type subunit 1|
|Background||Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||GLUH1; GLUR1; GLURA; GluA1; HBGR1|
|Protein Families||Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane|
|Protein Pathways||Amyotrophic lateral sclerosis (ALS), Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.