MARCH I (MARCH1) Rabbit Polyclonal Antibody

CAT#: TA329872

Rabbit Polyclonal Anti-MARCH1 Antibody

Product Images

WB Suggested Anti-MARCH1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Muscle

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-MARCH1 antibody: synthetic peptide directed towards the N terminal of human MARCH1. Synthetic peptide located within the following region: LQASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGT
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 31 kDa
• Gene Name: membrane associated ring-CH-type finger 1
• Database Link:
  NP_001159845
  Entrez Gene 55016 Human
  UniProt ID Q8TCQ1
• Background: MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
• Synonyms: MARCH-I; RNF171
• Note: Immunogen sequence homology: Dog: 100%; Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 100%

Reference Data

• Protein Families: Druggable Genome, Transmembrane