P2ry6 Rabbit Polyclonal Antibody

CAT#: TA329000

Rabbit polyclonal Anti-P2Y6 Receptor

Product Images

Western blot analysis of rat brain (lanes 1, 3) and rat heart (lanes 2, 4) lysates: 1, 2. Anti-P2Y6 Receptor antibody, (1:200). 3, 4. Anti-P2Y6 Receptor antibody, preincubated with the control peptide antigen.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:200-1:2000; IHC: 1:100-1:3,000; FC: 1:50-1:600
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide CQPHDLLQKLTAKWQRQRV, corresponding to amino acid residues 311-328 of rat P2Y6 receptor. Intracellular, C-terminus.
• Formulation: Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
• Reconstitution Method: Add 50 ul double distilled water (DDW) to the lyophilized powder.
• Purification: Affinity purified on immobilized antigen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: pyrimidinergic receptor P2Y6
• Database Link:
  NP_476465
  Entrez Gene 5031 HumanEntrez Gene 233571 MouseEntrez Gene 117264 Rat
  UniProt ID Q63371
• Background: The nucleotide receptor P2Y6 binds UDP, and is a member of the G-protein coupled receptor superfamily. P2Y6 agonists induce an inositol phosphate/Ca2+ response that is insensitive to pertussis toxin inhibition. P2Y6 is coupled to phospholipase C via Gq, and is also coupled to inhibition of N-type Ca2+ and M-type K+ channels. P2Y6 mRNA is expressed in various rat tissues, including lung, stomach, intestine, spleen, heart, and aorta. P2Y6 was reported to mediate contractions in human cerebral arteries. Alomone Labs is please to offer a highly specific antibody directed against the C-terminus domain of the rat P2Y6 receptor. Anti-P2Y6 Receptor antibody can be used in western blot analysis, indirect flow cytometry, immunoprecipitation, immunocytochemistry and immunohistochemistry. It has been designed to recognize P2Y6 from rat, mouse and human samples.
• Synonyms: MGC15335; P2Y6