ATG4B Rabbit Polyclonal Antibody

CAT#: TA328128

Rabbit polyclonal anti-ATG4B antibody (Center)

Product Images

ATG4B Antibody (Center) (Cat. #TA328128) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ATG4B antibody detected the ATG4B protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human (Predicted: Mouse, Zebrafish, Bovine, Chicken)
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This ATG4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-290 amino acids from the Central region of human ATG4B.
• Formulation: PBS with 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: autophagy related 4B cysteine peptidase
• Database Link:
  NP_847896
  Entrez Gene 66615 MouseEntrez Gene 23192 Human
  UniProt ID Q9Y4P1
• Background: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
• Synonyms: APG4B; AUTL1

Reference Data

• Protein Families: Protease
• Protein Pathways: Regulation of autophagy