PRC1 Mouse Monoclonal Antibody [Clone ID: 6G2]

CAT#: TA328062

Mouse Monoclonal anti-PRC1 Antibody

Product Images

Hela cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody reactive against PRC1 (clone 6G2). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system.

Specifications

Product Data

• Clone Name: 6G2
• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b, kappa
• Clonality: Monoclonal
• Immunogen: Amino Acid: 1-150
• Formulation: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
• Concentration: lot specific
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 72 kD
• Gene Name: protein regulator of cytokinesis 1
• Database Link:
  NP_955445
  Entrez Gene 9055 Human
  UniProt ID O43663
• Background: PRC1 (also known as protein regulator of cytokinesis 1 and mitotic spindle-associated CDK substrate) is a member of the MAP65/ASE1 family with a molecular weight of approximately 72 kD. PRC1 localization changes with cell-cycle position and can be found in the nucleus, the mitotic spindle, and the cell mid-body. PRC1 is a mitotic spindle-associated CDK substrate protein required for cytokinesis and maintenance of the spindle midzone. PRC1 can be modified by phosphorylation and has been shown to interact with Cdc2 and Cdk2. The 6G2 antibody recognizes the human PRC1 protein and has been shown to be useful for Western blotting.
• Synonyms: ASE1