Cyclin B1 (CCNB1) Mouse Monoclonal Antibody [Clone ID: V152]

CAT#: TA328039

Mouse Monoclonal anti-Cyclin B1 Antibody

Product Images

Western blot analysis of extracts from Hela (lane 1) and NIH/3T3 (lane 2) cells, using anti-Cyclin B1, V152.

Specifications

Product Data

• Clone Name: V152
• Applications: WB
• Recommended Dilution: WB, IF, IHC
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Hamster Cyclin B1
• Formulation: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.
• Concentration: lot specific
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cyclin B1
• Database Link:
  NP_114172
  Entrez Gene 268697 MouseEntrez Gene 891 Human
  UniProt ID P14635
• Background: Cyclin B1 belongs to the cyclin family, Cyclin AB subfamily, and predicted molecular weight 48 kD. Cyclin B1 is expressed ubiquitously in all eukaryotes and the level of cyclin B1 was minimal in G, began to rise in S phase, and is primarily cytoplasmic. Cyclin B1 moves into the nucleus just at the start of mitosis and associates with condensed chromosomes and the mitotic spindle. The level of cyclin B1 peaked at the G/M transition. Cyclin B1 is essential for the control of the cell cycle at the G2/M transition. The V152 monoclonal antibody recognizes human and mouse Cyclin B1 and has been shown to be useful for Western blotting. and immunohistochemistry (paraffin embedded tissue sections) of human and mouse cyclin B1.
• Synonyms: CCNB

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Cell cycle, Oocyte meiosis, p53 signaling pathway, Progesterone-mediated oocyte maturation