DNA PKcs (PRKDC) Rabbit Polyclonal Antibody

CAT#: TA327814

Rabbit Polyclonal Phospho-DNA-PK (Thr2647) Antibody (Phospho-specific)

Specifications

Product Data

• Recommended Dilution: IHC: 1:50-1:200; IF/ICC: 1:100-1:500
• Reactivities: Human
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human DNA-PK around the phosphorylation site of Threonine 2647
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: protein kinase, DNA-activated, catalytic polypeptide
• Database Link:
  NP_008835
  Entrez Gene 5591 Human
  UniProt ID P78527
• Background: The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q.
• Synonyms: DNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; IMD26; p350; XRCC7

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Cell cycle, Non-homologous end-joining