Papillary renal cell carcinoma (PRCC) Mouse Monoclonal Antibody [Clone ID: PN-15]

CAT#: TA327732

Mouse Monoclonal Renal Cell Carcinoma Antibody

Product Images

Immunohistochemistry staining of Paraffin Renal cell carcinoma tissue by Renal Cell Carcinoma antibody (dilution: 1:50 - 1:200; visualization of staining: Cytoplasmic, membranous)

Specifications

Product Data

• Clone Name: PN-15
• Applications: IHC
• Recommended Dilution: IHC: 1:50 - 1:200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: papillary renal cell carcinoma (translocation-associated)
• Database Link:
  NP_005964
  Entrez Gene 5546 Human
  UniProt ID Q92733
• Synonyms: RCCP1; TPRC
• Note: Anti-renal cell carcinoma (RCC) recognizes a 200 kD glycoprotein localized in the brush border of the proximal renal tubule.This antibody immunoreacts with approximately 90% of primary renal cell carcinomas and approximately 85% of metastatic renal cell carcinomas. Therefore, anti-RCC is a reliable tool for differentiating primary or metastatic renal cell carcinoma from non-renal tumors. It may be utilized as a marker for the differential diagnosis of eosinophilic renal tumors-granular variant of renal cell carcinoma, chromophobe renal cell carcinoma, and oncocytoma. Other tumors that may react with this antibody are parathyroid adenoma and an occasional breast carcinoma. Nephroblastoma, oncocytoma, mesoblastic nephroma, transitional cell carcinoma, and angiomyolipoma are not labeled with this antibody.

Reference Data

• Protein Families: Druggable Genome