ATG4A Rabbit Polyclonal Antibody

CAT#: TA327389

ATG4A Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using ATG4A antibody.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human ATG4A
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: autophagy related 4A cysteine peptidase
• Database Link:
  NP_840054
  Entrez Gene 666468 MouseEntrez Gene 678769 RatEntrez Gene 100910507 RatEntrez Gene 115201 Human
  UniProt ID Q8WYN0
• Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
• Synonyms: APG4A; AUTL2

Reference Data

• Protein Families: Protease
• Protein Pathways: Regulation of autophagy