RFC1 Rabbit Polyclonal Antibody

CAT#: TA327110

RFC1 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of MCF-7 cell lines, using RFC1 antibody.

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  Immunofluorescence analysis of MCF7 cell using RFC1 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000;IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human RFC1
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: replication factor C subunit 1
• Database Link:
  NP_002904
  Entrez Gene 19687 MouseEntrez Gene 89809 RatEntrez Gene 5981 Human
  UniProt ID P35251
• Background: This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3 end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011]
• Synonyms: A1; MHCBFB; PO-GA; RECC1; RFC; RFC140

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: DNA replication, Mismatch repair, Nucleotide excision repair