IL9 Rabbit Polyclonal Antibody

CAT#: TA326661

Rabbit Polyclonal IL-9 Antibody

Product Images

Western blot analysis of IL-9 in human spleen tissue lysate at 1 ug/ml.

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  Immunohistochemistry of IL-9 in human spleen tissue with IL-9 antibody at 5 ug/mL.

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  Immunofluorescence of IL-9 in human spleen tissue with IL-9 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: IL-9 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-9.
• Formulation: IL-9 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: IL-9 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 13 kDa; Observed: 22 kDa
• Gene Name: interleukin 9
• Database Link:
  NP_000581
  Entrez Gene 3578 Human
  UniProt ID P15248
• Background: Interleukin 9 (IL-9) is a cytokine secreted by TH2 lymphocytes that acts as a regulator of a variety of hematopoietic cells, stimulates cell proliferation and prevents apoptosis (1,2). It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins (3). The IL-9 gene has been identified as a candidate gene for asthma (4). Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness (5).
• Synonyms: HP40; IL-9; P40

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Asthma, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway