Kcnb1 Mouse Monoclonal Antibody [Clone ID: S4-11]

CAT#: TA326553

Mouse Monoclonal Anti-Kv2.1 Antibody

Product Images

IHC analysis of Kv2.1 tested on mouse brain hippocampus showing strong membrane staining of neurons, using a dilution of the antibody

Specifications

Product Data

• Clone Name: S4-11
• Applications: IHC
• Recommended Dilution: WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
• Reactivities: Human, Mouse, Rat, Monkey
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Bacterially expressed GST Bacterially expressed GSTfusion protein corresponding to amino acids 509-853 of rat KV2.1
• Formulation: PBS pH7.4, 50% glycerol
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: potassium voltage-gated channel subfamily B member 1
• Database Link:
  NP_037318
  Entrez Gene 3745 HumanEntrez Gene 16500 MouseEntrez Gene 703520 MonkeyEntrez Gene 25736 Rat
  UniProt ID P15387
• Background: Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alphasubunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1- KV4 subfamilies generate functional K+ channels in a homotetrameric configuration. The KV2 subfamily consists of KV2.1 and KV2.2, and both have very similar properties. Members of the KV2 subfamily are widely expressed in neuronal tissues. They have also been reported in neurons in the dorsal root ganglia .
• Synonyms: DRK1; h-DRK1; Kv2.1
• Note: Detects ~105-125kDa. Recognizes the Shab related a- subunit Kv2.1.