Gria2 Mouse Monoclonal Antibody [Clone ID: S21-32]

CAT#: TA326535

Mouse Monoclonal Anti-GluR2 Antibody

Product Images

Western blot analysis of GluR2 on rat brain membrane tissues using a 1:1000 dilution of the antibody

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  IHC analysis of GluR2 using the antibody, tested on mouse cerebellum. Staining of neurons and fibers.

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  IHC analysis of GluR2 using the antibody, tested on mouse cerebellum. Staining of hippocampus: only some neurons appear to be positive to the antibody.

Specifications

Product Data

• Clone Name: S21-32
• Applications: IHC, WB
• Recommended Dilution: WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 834-883 (cytoplasmic C-terminus) of rat GluR2
• Formulation: PBS pH7.4, 50% glycerol
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: glutamate ionotropic receptor AMPA type subunit 2
• Database Link:
  NP_058957
  Entrez Gene 2891 HumanEntrez Gene 14800 MouseEntrez Gene 29627 Rat
  UniProt ID P19491
• Background: The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers . GluR2 is possibly the most important AMPA receptor subunit, responsible for AMPA receptor rectifying properties, control of ion flow and in particular, the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2 form, containing a critical arginine residue in the transmembrane region 2 domain, thereby rendering native AMPA receptors impermeable to calcium .
• Synonyms: GluA2; gluR-B; GluR-K2; GLUR2; GluR2; GLURB; HBGR2
• Note: Detects ~90kDa.