AHA1 (AHSA1) Rat Monoclonal Antibody [Clone ID: 25F2.D10]

CAT#: TA326465

Rat Monoclonal Anti-Aha4 Antibody

Product Images

Western blot analysis of Aha1 in a human cell line mix, using a 1:1000 dilution of the antibody

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  IF of Aha1 tested on HeLa cell lysates.

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  IP of Aha1 tested on HeLa cell lysates.

Specifications

Product Data

• Clone Name: 25F2.D10
• Applications: IF, IP, WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Mouse, Rat
• Host: Rat
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Immunogen: Mouse Aha1
• Formulation: 0.02M potassium phosphate, 0.15M sodium chloride, pH7.2
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: activator of Hsp90 ATPase activity 1
• Database Link:
  NP_036243
  Entrez Gene 217737 MouseEntrez Gene 681996 RatEntrez Gene 10598 Human
  UniProt ID O95433
• Background: Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding . It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) . Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors .
• Synonyms: AHA1; C14orf3; p38
• Note: Detects ~38kDa. Can run up to 45kDa on SDS Page