TXNDC5 Mouse Monoclonal Antibody [Clone ID: 2E7/7]

CAT#: TA326409

Mouse monoclonal EndoPDI Antibody

Specifications

Product Data

• Clone Name: 2E7/7
• Recommended Dilution: WB: 1:200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Synthesized peptide - 12 amino acids long (ADGEDGQDPHSK) corresponding to residues 52 - 63 of the EndoPDI protein
• Formulation: PBS pH7.4, 50% glyercol and 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: thioredoxin domain containing 5
• Database Link:
  NP_071368
  Entrez Gene 81567 Human
  UniProt ID Q8NBS9
• Background: Endothelial protein disulfide isomerase (EndoPDI) is a thioredoxin member of the protein disulfide isomerase family of chaperones. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells. EndoPDI mRNA and protein expression is induced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia .
• Synonyms: EndoPDI; ERP46; Hcc-2; MGC3178; thioredoxin domain containing 5; UNQ364
• Note: Detects a protein with a mass of ~48kDa corresponding to EndoPDI

Reference Data

• Protein Families: Druggable Genome