Metabotropic Glutamate Receptor 2 (GRM2) Rabbit Polyclonal Antibody

CAT#: TA326002

Rabbit Polyclonal GluR2 (Ser880) Antibody (Phospho-specific)

Product Images

Western blot analysis of GluR2 phosphorylation expression in Mouse braintissue lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human GluR2 around the phosphorylation site of Serine 880
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 99 kDa
• Gene Name: glutamate metabotropic receptor 2
• Database Link:
  NP_000830
  Entrez Gene 24415 RatEntrez Gene 108068 MouseEntrez Gene 2912 Human
  UniProt ID Q14416
• Background: GluR2 an integral membrane protein belonging to the glutamate-gated ion channel family. L-glutamate (Glu) acts as an excitatory neurotransmitter at many synapses in the central nervous system. Glutamate receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.
• Synonyms: GLUR2; GPRC1B; mGlu2; MGLUR2

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction