GABA A Receptor beta 1 (GABRB1) Rabbit Polyclonal Antibody

CAT#: TA325493

Rabbit Polyclonal GABA-RB (Ser434) Antibody (Phospho-specific)

Product Images

Western blot analysis of GABA-RB phosphorylation expression in COS7 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human GABA-RB around the phosphorylation site of Serine 434
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: gamma-aminobutyric acid type A receptor beta1 subunit
• Database Link:
  NP_000803
  Entrez Gene 14400 MouseEntrez Gene 25450 RatEntrez Gene 2560 Human
  UniProt ID P18505
• Background: GABRB1 GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
• Synonyms: beta 1; gamma-aminobutyric acid (GABA) A receptor

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction