ADH1B Rabbit Polyclonal Antibody

CAT#: TA323599

Anti-ADH1B Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Raji cell lysate Primary antibody: TA323599 (ADH1B Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA323599 (ADH1B Antibody) at dilution 1/55 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA323599 (ADH1B Antibody) at dilution 1/55, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Raji cell lysate
  IHC: 50-300
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 226-338 amino acids of human alcohol dehydrogenase 1B (class I), beta polypeptide
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 40 kDa
• Gene Name: alcohol dehydrogenase 1B (class I), beta polypeptide
• Database Link:
  NP_000659
  Entrez Gene 125 Human
  UniProt ID P00325
• Background: The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates; including ethanol; retinol; other aliphatic alcohols; hydroxysteroids; and lipid peroxidation products. This encoded protein; consisting of several homo- and heterodimers of alpha; beta; and gamma subunits; exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha; beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.
• Synonyms: ADH2; HEL-S-117

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Fatty acid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tyrosine metabolism