GCSF Receptor (CSF3R) Rabbit Polyclonal Antibody

CAT#: TA323571

Anti-CSF3R Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA323571 (CSF3R Antibody) at dilution 1/12 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA323571 (CSF3R Antibody) at dilution 1/12, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 15-50
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm, Cell membrane
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 470-484 amino acids of human colony stimulating factor 3 receptor (granulocyte)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: colony stimulating factor 3 receptor
• Database Link:
  NP_000751
  Entrez Gene 1441 Human
  UniProt ID Q99062
• Background: The protein encoded by this gene is the receptor for colony stimulating factor 3; a cytokine that controls the production; differentiation; and function of granulocytes. The encoded protein; which is a member of the family of cytokine receptors; may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome; also known as severe congenital neutropenia.
• Synonyms: CD114; GCSFR

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Pathways in cancer