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Pirh2 (RCHY1) Rabbit Polyclonal Antibody
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USD 436.00
USD 200.00
USD 867.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 25-100 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm |
| Reactivities | Human, Mouse |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | ring finger and CHY zinc finger domain containing 1 |
| Database Link | |
| Background | The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins; including TP53; HDAC1 and CDKN1B; thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Synonyms | ARNIP; CHIMP; PIRH2; PRO1996; RNF199; ZCHY; ZNF363 |
| Reference Data | |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | p53 signaling pathway, Ubiquitin mediated proteolysis |
Documents
| Product Manuals |
| FAQs |
| SDS |
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