PGA3 Rabbit Polyclonal Antibody

CAT#: TA323323

Anti-PGA3 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 42 kDa. Positive control: Human liver cancer tissue lysate. Recommended dilution: 1/1000-5000. (Gel: 10%SDS-PAGE Lysate: 60 ug per lane Primary antibody: 1/700 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

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  Predicted cell location: Cytoplasm. Positive control: Human breast cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using PGA3 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:1000-5000, WB: 1:1000-5000, IHC: 1:25-100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 112-125 amino acids of Human pepsinogen 3, group I (pepsinogen A)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 42 kDa
• Gene Name: pepsinogen 3, group I (pepsinogen A)
• Database Link:
  NP_001073275
  Entrez Gene 643834 Human
  UniProt ID P0DJD8
• Background: The genes coding for human pepsinogen (PGA3; PGA4; and PGA5) were assigned to chromosome region 11q13 by in situ hybridization. Previously we localized the PGA gene complex to a centromeric region of chromosome 11 (p11----q13) by Southern blot analysis of mouse-human somatic cell hybrids.?Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred; many others are also cleaved to some extent.
• Synonyms: PGA4; PGA5

Reference Data

• Protein Families: Druggable Genome