PSD95 (DLG4) Rabbit Polyclonal Antibody

CAT#: TA323182

Anti-DLG4 Rabbit Polyclonal Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA323182 (DLG4 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA323182 (DLG4 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human ovarian cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 93-106 amino acids of Human discs, large homolog 4 (Drosophila)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: discs large MAGUK scaffold protein 4
• Database Link:
  NP_001356
  Entrez Gene 13385 MouseEntrez Gene 29495 RatEntrez Gene 1742 Human
  UniProt ID P78352
• Background: This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein; DLG2; and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors; ion channels; and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: PSD95; SAP-90; SAP90

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Huntington's disease