Ghrelin Receptor (GHSR) Rabbit Polyclonal Antibody

CAT#: TA322789

Anti-GHSR Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane: A549 cells Primary antibody: TA322789 (GHSR Antibody) at dilution 1/1500 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1000-3000
  WB positive control: A549 cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 18-32 amino acids of Human growth hormone secretagogue receptor
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 41 kDa
• Gene Name: growth hormone secretagogue receptor
• Database Link:
  NP_004113
  Entrez Gene 84022 RatEntrez Gene 208188 MouseEntrez Gene 2693 Human
  UniProt ID Q92847
• Background: This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript; 1a; excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however; it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
• Synonyms: GHDP

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction