14-3-3 theta (YWHAQ) Rabbit Polyclonal Antibody

CAT#: TA322463

Anti-YWHAQ Rabbit Polyclonal Antibody

Product Images

Gel: 10+12%SDS-PAGE Lysate: 40 μg Lane 1-4: Mouse brain tissue A549 cells human lymphoma tissue hela cells Primary antibody: TA322463 (YWHAQ Antibody) at dilution 1/950 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA322463 (YWHAQ Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA322463 (YWHAQ Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA322463 (YWHAQ Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA322463 (YWHAQ Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Mouse brain tissue, A549 cells and human lymphoma tissue, hela cells
  IHC: 25-100
  Positive control: Human ovarian cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 140-154 amino acids of Human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 28 kDa
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
• Database Link:
  NP_006817
  Entrez Gene 22630 MouseEntrez Gene 25577 RatEntrez Gene 10971 Human
  UniProt ID P27348
• Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals; and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic; however; there is no correlation between the repeat number and the disease.?
• Synonyms: 1C5; 14-3-3; HS1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis, Pathogenic Escherichia coli infection