AKAP8L Rabbit Polyclonal Antibody

CAT#: TA322383

Anti-AKAP8L Rabbit Polyclonal Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane 1-2: Hela cells mouse brain tissue Primary antibody: TA322383 (AKAP8L Antibody) at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA322383 (AKAP8L Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA322383 (AKAP8L Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela cells and mouse brain tissue
  IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Nucleus, Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide peptide corresponding to a region derived from 627-640 amino acids of human A kinase (PRKA) anchor protein 8-like
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 72 kDa
• Gene Name: A-kinase anchoring protein 8 like
• Database Link:
  NP_055186
  Entrez Gene 54194 MouseEntrez Gene 26993 Human
  UniProt ID Q9ULX6
• Background: A-kinase anchor protein 8-like is an enzyme that in humans is encoded by the AKAP8L gene. AKAP8L has been shown to interact with Thymopoietin[4][5] and DHX9. Could play a role in constitutive transport element (CTE)-mediated gene expression. Does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May regulate the initiation phase of DNA replication when associated with TMPO-beta.
• Synonyms: HA95; HAP95; NAKAP; NAKAP95

Reference Data

• Protein Families: Druggable Genome