MMP26 Rabbit Polyclonal Antibody

CAT#: TA322219

Anti-MMP26 Rabbit Polyclonal Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: Human placenta tissue lysate Primary antibody: TA322219 (MMP26 Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA322219 (MMP26 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA322219 (MMP26 Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human placenta tissue lysate
  IHC: 30-150
  Positive control: Human tonsil
  Predicted cell location: Secreted
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 243-261 amino acids of Human matrix metallopeptidase 26
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 30 kDa
• Gene Name: matrix metallopeptidase 26
• Database Link:
  NP_068573
  Entrez Gene 56547 Human
  UniProt ID Q9NRE1
• Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; and tissue remodeling; as well as in disease processes; such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen; fibronectin; fibrinogen; casein; vitronectin; alpha 1-antitrypsin; alpha 2-macroglobulin; and insulin-like growth factor-binding protein 1; and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.
• Synonyms: MGC126590; MGC126592

Reference Data

• Protein Families: Druggable Genome, Secreted Protein