ANGPTL3 Rabbit Polyclonal Antibody

CAT#: TA321837

Anti-ANGPTL3 Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: A375 cell lysate Primary antibody: TA321837 (ANGPTL3 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA321837 (ANGPTL3 Antibody) at dilution 1/30. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: A375 cell lysate
  IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 300 amino acids of Human Angiopoietin-related protein 3
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54 kDa
• Gene Name: angiopoietin like 3
• Database Link:
  NP_055310
  Entrez Gene 27329 Human
  UniProt ID Q9Y5C1
• Background: The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver; and has the characteristic structure of angiopoietins; consisting of a signal peptide; N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins; and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
• Synonyms: ANG-5; ANGPT5; ANL3; FHBL2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein