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ASCL1 Rabbit Polyclonal Antibody
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USD 436.00
USD 200.00
USD 867.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Nucleus |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 215-228 amino acids of human achaete-scute complex homolog 1 (Drosophila) |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | achaete-scute family bHLH transcription factor 1 |
| Database Link | |
| Background | This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. |
| Synonyms | ASH1; bHLHa46; HASH1; MASH1 |
| Reference Data | |
| Protein Families | Druggable Genome, Transcription Factors |
Documents
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