CTNNBL1 Rabbit Polyclonal Antibody

CAT#: TA319966

Rabbit Polyclonal CTTNBL1 Antibody

Product Images

Western blot analysis of CTNNBL1 in human brain tissue lysate with CTNNBL1 antibody at (A) 1 and (B) 2 ug/mL.

• 

  Immunohistochemistry of CTNNBL1 in mouse brain tissue with CTNNBL1 antibody at 5 ug/mL.

• 

  Immunofluorescence of CTNNBL1 in mouse brain tissue with CTNNBL1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: CTTNBL1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human CTTNBL1.
• Formulation: CTTNBL1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: CTTNBL1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: catenin beta like 1
• Database Link:
  NP_110517
  Entrez Gene 66642 MouseEntrez Gene 296320 RatEntrez Gene 56259 Human
  UniProt ID Q8WYA6
• Background: CTTNBL1 Antibody: The Beta-catenin-like protein 1 (CTNNBL1) contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs, as well as Armadillo/beta-catenin-like repeats. Transient expression of CTNNBL1 resulted in translocation to the nucleus and apoptosis, suggesting it may be involved in the apoptotic pathway. CTNNBL1 interacts with the Prp19 complex of the spliceosome and the Ig class switching enzyme activation-induced deaminase (AID) and had been suggested to play a role in antibody-diversification and class switching, but recent studies have shown CTNNBL1 to be dispensable for Ig class switch recombination. Other studies have identified CTTNBL1 as a novel gene for obesity.
• Synonyms: C20orf33; dJ633O20.1; NAP; P14L; PP8304

Reference Data

• Protein Pathways: Spliceosome