AMPK alpha 2 (PRKAA2) Rabbit Polyclonal Antibody

CAT#: TA309997

Rabbit anti-PRKAA2 (AMPK1/AMPK2, Phospho-Ser485/Ser491) polyclonal antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from HeLa cells untreated or treated with heat shock (30min), using AMPK1/AMPK2 (phospho-Ser485/Ser491) antibody.

• 

  Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using AMPK1/AMPK2 (phospho-Ser485/Ser491) antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:1000, IHC: 1:50~1:100
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from humanAMPK1/AMPK2 around the phosphorylation site of serine 485/491 (S-G- SP-V-S).
• Formulation: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: protein kinase AMP-activated catalytic subunit alpha 2
• Database Link:
  NP_006243
  Entrez Gene 78975 RatEntrez Gene 108079 MouseEntrez Gene 5563 Human
  UniProt ID P54646
• Synonyms: AMPK; AMPK2; AMPKa2; PRKAA

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Adipocytokine signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin signaling pathway, mTOR signaling pathway, Regulation of autophagy