Proteasome subunit alpha type 6 (PSMA6) Rabbit Polyclonal Antibody

CAT#: TA308943

Rabbit Polyclonal antibody to Proteasome 20S alpha 6 (proteasome (prosome, macropain) subunit, alpha type, 6)

Product Images

Sample (30 ug of whole cell lysate). A: 293T. B: A431. C: H1299. D: Hela. 12% SDS PAGE. TA308943 diluted at 1:1000.

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  Proteasome 20S alpha 6 antibody detects PSMA6 protein by Western blot analysis. A. 50 ug mouse liver lysate/extract. 12 % SDS-PAGE. Proteasome 20S alpha 6 antibody (TA308943) dilution: 1:1000

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  Proteasome 20S alpha 6 antibody detects PSMA6 protein by Western blot analysis. A. 50 ug rat liver lysate/extract. 12 % SDS-PAGE. Proteasome 20S alpha 6 antibody (TA308943) dilution: 1:1000

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  Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using 20S Proteasome alpha6 (TA308943) antibody at 1:100 dilution.

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  Proteasome 20S alpha 6 antibody detects Proteasome 20S alpha 6 protein at cytosol and nucleus on mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. Proteasome 20S alpha 6 antibody (TA308943) dilution: 1:500.

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  Proteasome 20S alpha 6 antibody detects Proteasome 20S alpha 6 protein at cytosol and nucleus on mouse urinary bladder by immunohistochemical analysis. Sample: Paraffin-embedded mouse urinary bladder. Proteasome 20S alpha 6 antibody (TA308943) dilution: 1

• Proteasome 20S alpha 6 antibody detects Proteasome 20S alpha 6 protein at cytosol and nucleus on mouse lung by immunohistochemical analysis. Sample: Paraffin-embedded mouse lung. Proteasome 20S alpha 6 antibody (TA308943) dilution: 1:500.

• Immunofluorescence analysis of paraformaldehyde-fixed A431, using 20S Proteasome alpha6 (TA308943) antibody at 1:200 dilution.

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Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse (Predicted: Chimpanzee, Bovine, Rhesus Monkey)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment contain a sequence corresponding to a region within amino acids 57 and 246 of Proteasome 20S alpha 6
• Formulation: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 27 kDa
• Gene Name: proteasome subunit alpha 6
• Database Link:
  NP_002782
  Entrez Gene 26443 MouseEntrez Gene 5687 Human
  UniProt ID P60900
• Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq]
• Synonyms: IOTA; p27K; PROS27
• Note: Seq homology of immunogen across species: Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)

Reference Data

• Protein Families: Druggable Genome, Protease, Stem cell - Pluripotency
• Protein Pathways: Proteasome