Fukutin (FKTN) Rabbit Polyclonal Antibody

CAT#: TA308879

Rabbit Polyclonal antibody to Fukutin (fukutin)

Product Images

Sample (30 ug of whole cell lysate). A: H1299. B: Hela. 10% SDS PAGE. TA308879 diluted at 1:1000.

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  Immunofluorescence analysis of methanol-fixed HeLa, using Fukutin (TA308879) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Mouse, Rat)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 222 and 461 of Fukutin (Uniprot ID#O75072)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54 kDa
• Gene Name: fukutin
• Database Link:
  NP_001073270
  Entrez Gene 246179 MouseEntrez Gene 362520 RatEntrez Gene 2218 Human
  UniProt ID O75072
• Background: The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
• Synonyms: CMD1X; FCMD; LGMD2M; MDDGA4; MDDGB4; MDDGC4
• Note: Seq homology of immunogen across species: Mouse (90%), Rat (91%)

Reference Data

• Protein Families: Transmembrane