Selenophosphate synthetase 2 (SEPHS2) Rabbit Polyclonal Antibody

CAT#: TA308431

Rabbit polyclonal antibody to SEPHS2 (selenophosphate synthetase 2)

Product Images

Sample (30ug whole cell lysate). A:HeLa S3. 7.5% SDS PAGE. TA308431 diluted at 1:1000

• 

  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using SEPHS2 (TA308431) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Chimpanzee)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 186 and 448 of SEPHS2 (Uniprot ID#Q99611)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 47 kDa
• Gene Name: selenophosphate synthetase 2
• Database Link:
  NP_036380
  Entrez Gene 22928 Human
  UniProt ID Q99611
• Background: This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop. Alternatively spliced transcripts have been identified, but their biological validity has not been determined. [provided by RefSeq]
• Synonyms: SPS2; SPS2b
• Note: Seq homology of immunogen across species: Chimpanzee (100%)

Reference Data

• Protein Pathways: Metabolic pathways, Selenoamino acid metabolism