HRH2 Rabbit Polyclonal Antibody

CAT#: TA308415

Rabbit Polyclonal antibody to Histamine H2 Receptor (histamine receptor H2)

Product Images

Histamine H2 Receptor antibody [N1], N-term detects HRH2 protein by Western blot analysis. A. 30 ug U87-MG whole cell lysate/extract. B. 30 ug SK-N-SH whole cell lysate/extract. 10 % SDS-PAGE. Histamine H2 Receptor antibody [N1], N-term (TA308415) dilutio

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  Immunohistochemical analysis of paraffin-embedded H520 xenograft, using Histamine H2 Receptor (TA308415) antibody at 1:100 dilution.

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  Immunofluorescence analysis of methanol-fixed HeLa, using Histamine H2 Receptor (TA308415) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: FACS:; ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Chimpanzee, Rhesus Monkey)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 45 of Histamine H2 Receptor (Uniprot ID#P25021)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 40 kDa
• Gene Name: histamine receptor H2
• Database Link:
  NP_001124527
  Entrez Gene 3274 Human
  UniProt ID P25021
• Background: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: H2R
• Note: Seq homology of immunogen across species: Rhesus Monkey (100%), Chimpanzee (100%)

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction