CD70 Rabbit Polyclonal Antibody

CAT#: TA308292

Rabbit polyclonal antibody to CD27L (CD27L (CD70)) (CD27L (CD70) molecule)

Product Images

Sample (30 ug of whole cell lysate). A: JurKat. 12% SDS PAGE. CD27L (CD70) antibody. TA308292 diluted at 1:1000.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human (Predicted: Mouse, Rat, Pig)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 129 and 193 of CD70 (Uniprot ID#P32970)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 21 kDa
• Gene Name: CD70 molecule
• Database Link:
  NP_001243
  Entrez Gene 21948 MouseEntrez Gene 301132 RatEntrez Gene 970 Human
  UniProt ID P32970
• Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq]
• Synonyms: CD27L; CD27LG; TNFSF7
• Note: Seq homology of immunogen across species: Mouse (80%), Rat (80%), Pig (87%)

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction