CASQ2 Rabbit Polyclonal Antibody

CAT#: TA308184

Rabbit polyclonal antibody to Calsequestrin-2 (calsequestrin 2 (cardiac muscle))

Product Images

Calsequestrin 2 antibody detects Calsequestrin 2 protein by western blot analysis. A. 30 ug HCT116 whole cell lysate/extract. 10 % SDS-PAGE. Calsequestrin 2 antibody (TA308184) dilution: 1:1000

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  Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using Calsequestrin-2 (TA308184) antibody at 1:500 dilution.

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  Calsequestrin-2 antibody detects Calsequestrin-2 protein at cytosol on mouse muscle by immunohistochemical analysis. Sample: Paraffin-embedded mouse muscle. Calsequestrin-2 antibody (TA308184) dilution: 1:500.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Cow, Rabbit, Rat)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment contain a sequence corresponding to a region within amino acids 124 and 388 of Calsequestrin 2 (Uniprot ID#O14958)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: calsequestrin 2
• Database Link:
  NP_001223
  Entrez Gene 29209 RatEntrez Gene 845 Human
  UniProt ID O14958
• Background: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq]
• Synonyms: PDIB2
• Note: Seq homology of immunogen across species: Rat (96%), Rabbit (96%), cow (95%)

Reference Data

• Protein Families: Druggable Genome