ASS1 Rabbit Polyclonal Antibody

CAT#: TA308171

Rabbit Polyclonal antibody to ASS1 (argininosuccinate synthetase 1)

Product Images

ASS1 antibody detects ASS1 protein by Western blot analysis. A. 30 ug A431 whole cell lysate/extract. 10 % SDS-PAGE. ASS1 antibody (TA308171) dilution: 1:1000

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  Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using ASS1 (TA308171) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 198 of ASS1 (Uniprot ID#P00966)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 47 kDa
• Gene Name: argininosuccinate synthase 1
• Database Link:
  NP_000041
  Entrez Gene 445 Human
  UniProt ID P00966
• Background: The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
• Synonyms: ASS; CTLN1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways