GIRK1 (KCNJ3) Rabbit Polyclonal Antibody

CAT#: TA308050

Rabbit polyclonal antibody to GIRK1 (potassium inwardly-rectifying channel, subfamily J, member 3)

Product Images

Sample (30 ug of whole cell lysate). A:A431. B: H1299. C: Hela. 7.5% SDS PAGE. TA308050 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded DU145 xenograft, using GIRK1 (TA308050) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Guinea Pig, Rhesus Monkey)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 248 and 501 of GIRK1 (Uniprot ID#P48549)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 57 kDa
• Gene Name: potassium voltage-gated channel subfamily J member 3
• Database Link:
  NP_002230
  Entrez Gene 3760 Human
  UniProt ID P48549
• Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq]
• Synonyms: GIRK1; KGA; KIR3.1
• Note: Seq homology of immunogen across species: Rhesus Monkey (100%), Guinea pig (100%)

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane