Aminoacylase 1 (ACY1) Rabbit Polyclonal Antibody

CAT#: TA308034

Rabbit polyclonal antibody to Aminoacylase-1 (aminoacylase 1)

Product Images

Sample (30 ug of whole cell lysate). A: H1299. 10% SDS PAGE. TA308034 diluted at 1:1000.

• 

  Aminoacylase 1 antibody [N2C3-2] detects Aminoacylase-1 protein at cytoplasm on placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. Aminoacylase 1 antibody [N2C3-2] (TA308034) dilution: 1:100.

• 

  Immunofluorescence analysis of paraformaldehyde-fixed A431, using Aminoacylase-1 (TA308034) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Mouse, Pig, Rat, Bovine)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 89 and 366 of Aminoacylase 1 (Uniprot ID#Q03154)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: aminoacylase 1
• Database Link:
  NP_000657
  Entrez Gene 109652 MouseEntrez Gene 300981 RatEntrez Gene 95 Human
  UniProt ID Q03154
• Background: Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes. [provided by RefSeq]
• Synonyms: ACY-1; ACY1D; HEL-S-5
• Note: Seq homology of immunogen across species: Mouse (85%), Pig (86%), Rat (86%), Bovine (87%)

Reference Data

• Protein Families: Protease
• Protein Pathways: Arginine and proline metabolism, Metabolic pathways