IVD Rabbit Polyclonal Antibody

CAT#: TA308023

Rabbit Polyclonal antibody to IVD (isovaleryl Coenzyme A dehydrogenase)

Product Images

Sample (50 ug of whole cell lysate). A: Mouse brain. 10% SDS PAGE. TA308023 diluted at 1:1000.

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  IVD antibody detects IVD protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. 10 % SDS-PAGE. IVD antibody (TA308023) dilution: 1:1000

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  Sample (30 ug of whole cell lysate). A: Hela. B: JurKat. 10% SDS PAGE. TA308023 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded Breast ca, using IVD (TA308023) antibody at 1:250 dilution.

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  Immunofluorescence analysis of methanol-fixed HeLa, using IVD (TA308023) antibody at 1:200 dilution.

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Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 222 of IVD (Uniprot ID#P26440)
• Formulation: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: isovaleryl-CoA dehydrogenase
• Database Link:
  NP_002216
  Entrez Gene 56357 MouseEntrez Gene 3712 Human
  UniProt ID P26440
• Background: Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. [provided by RefSeq]
• Synonyms: ACAD2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Valine, leucine and isoleucine degradation